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Categories
» Industrial Nanotechnology Products
» Nanoscale chemicals and colloidal solutions
| DNT sells and licenses more than 200 of its products to scientific innovators in academia, government and private institutions. |
| Country: |
United States of America |
| Link to your website: |
http://dnanotech.com |
Description:
Dendrimer molecules represent an exciting new class of macromolecular architecture and key components in the emerging area of nanoscale science and technology. The rapidly accelerating research and development activities in dendrimers and dendritic materials provides critically needed nanoscale bulding blocks suitable for the development of high performance materials. Dendrimers are widely recognized as the most versatile, compositionally and structurally controlled nanoscale building blocks available.
Dendrimers are nanoparticles that can be precisely designed and manufactured for a wide variety of applications. They are formed by the addition of shells of branched molecules to a central core.
By adjusting chemical properties of the core, the shells, and especially the surface layer, dendrimers can be tailored to fit the needs of specific applications. Their precise and designable architecture, tunable solubility, low toxicity and immunogenicity, and bioattachment capability make dendrimers the ideal building blocks for biotechnology. Dendrimers are an enabling technology.
Because of their precise architecture and construction, dendrimers possess inherently valuable physical, chemical and biological properties. These properties include:
Efficient membrane transport — Dendrimers have demonstrated rapid transport capabilities across biological membranes
High loading capacity — Dendrimer structures can be used to carry and store a wide range of metals, organic or inorganic molecules by encapsulation and absorption.
High uniformity and purity — The synthetic process used produces dendrimers with uniform sizes, precisely defined surface functionality, and very low impurity levels.
Low toxicity — Most dendrimer systems display very low cytotoxicity levels.
Low immunogenicity — Dendrimers commonly manifest a very low or negligible immunogenic response when injected or used topically.
In summary, DNT’s dendrimer-based technologies provide the necessary interface between chemistry and biology. They have the ability to act as appropriate containers for delivery vehicles in vitro and in vivo due to their specific, precise and predictable custom designed dendritic polymer architectures. |
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